2-Hydroxy Phosphonoacetic Acid (HPAA) 2018-09-25T03:30:52+00:00

Project Description


2-Hydroxy Phosphonoacetic Acid(HPAA)

Synonyms: HPA; Hydroxyphosphono-Acetic Acid; Phosphonoglycolic Acid; Belcor 575; Multicor 75; Mayoquest 1750; Unisperse 175; Heparanase-1; Snailagglutinin;

The main HPAA production route is as follow.

Phosphorus acid solution reacts with glyoxylic at 100-110℃ for 4-10hours. And then input water to prepare HPAA aqueous solution.

This reaction can be 1-step forward and starts from PCl3 hydrolysis. Some research is studying to use microwave irradiation to replace heating process for reducing the energy consumption and reaction time.

CAS No. 23783-26-8
Molecular Formula: C2H5O6P
Molecular weight: 156
Structural Formula:


HPAA is chemically stable, hard to be hydrolyzed, hard to be destroyed by acid or alkali, safety in use, no toxicity, no pollution. HPAA can improve zinc solubility. HPAA has superior performance than those commonly used phosphonates like HEDP and EDTMP  (5 – 8 times better). Sometimes HPAA can even replace molybdate and its derivatives. The good efficiency at low concentration enables HPAA usually used at PPM level. HPAA is water soluble and can increase Zn solubility. Its effect can be further improved when built with Zn salts or polymer.

AppearanceDark amber transparent liquid
Solid content %50.0 min
pH (1% solution)3.0 max
Density (20℃) g/cm31.30 min

HPAA is mainly used as cathode corrosion inhibitor in the oilfield refill water system in fields such as steel & iron, petrochemical, power plant, and medical industries. When built with a zinc salt, the effect is even better.

As a corrosion inhibitor, HPAA is mainly applied in cooling water/industrial water system of oilfield, petrochemical plant and power plant. It is also used for metal surface treatment in steel.

Package and Storage:

200L plastic drum, IBC (1000L), customers’ requirement. Storage for one year in shady room and dry place.

Transport info: Corrosive. IMO class 8, UN 3265