2 2-Dibromo-3-Nitrilo-Propionamide (DBNPA)


DBNPA is white crystals. The melting point is 125°C. It can soluble in acetone, polyethylene glycol, benzene, ethanol and the like. DBNPA is stable in acidic conditions and decomposed in alkaline conditions or in the presence of hydrogen sulfide. DBNPA is an efficient germicide for recycling water system.

DBNPA can penetrate in the cytocyst of microbes quickly. And then kill them by reacting with some proteins in it. In this way, it can stop the redox of cells. It has a good stripping property, little poison, and no foam in the system. The organic solutions can miscible with water.

CAS No.: 10222-01-2

Molecular Formula: C3H2ON2Br2

Molecular Weight: 241.84

Structural Formula:



Assay99% Min.
Melting Point122~128°C
pH (1% Aqueous Solution)4.0~6.5
Loss on Drying1% Max.


Biocides are in a broad spectrum. 2,2-Dibromo-3-Nitrilo-Propionamide is widely used in the industrial circulating water system, large air-condition and the large center of sewage treatment. It is used to eliminate microorganism and alga and shuck off clay. DBNPA is also used in the process of papermaking to prevent reducing the quality of paper by a generation of microorganism.

It is suitable for metal cutting of cooling liquor, recovery system of oil, latex, and ply-woods as anti-spy biocides. DBNPA has the following advantages.

  1. Easy to handle.
  2. No unusual oxidation hazards.
  3. Similar performance and safety in paper and oilfield applications.
  4. Slime control in the wet-end of the paper mill and performs exceptionally well against slime-forming bacteria.

DBNPA has exhibited outstanding efficiency against in bio-films and against a broad spectrum of bacteria, fungus, and yeasts.

Additionally, DBNPA series products are used in the short-term preservation of coatings and coating additives. Such as latex, starch and mineral slurries. It is a quick-kill biocide that is broad-spectrum and does not contain or release formaldehyde.

Package and Storage:

25 kg fiber drum. Keep dry.

Application of DBNPA Biocide in Circulating Cooling Water System

System overview:

A refinery circulating water system. The volume of retained water is 4000 m3. The volume of circulating water is 4500 m3/h. It has low concentration factor. The slime breeds severely. The operation is not good. Microbial and slime failures are the biggest problems in the system.

Microbial control program:

Chemical NameDosing ConcentrationDosing Method
Brominated oxidizing biocide20~30 ppm per dayContinuous dosing
DBNPA10~15 ppm once a weekImpact dosing
RemarksThe original scheme uses an isothiazide non-oxidizing fungicide, which is added once a week, and the concentration is 100 ppm, and the others are the same.

DBNPA is used as a non-oxidizing bactericide. In combination with bromine-based bactericides under frequent leakage conditions, the microbial control of the system can be improved. The specific plan is as follows.

Process test results:

Test ItemsResidual Chlorine, (mg/L)Heterotrophic bacteria, (pieces/mL)Mud amount (mL/m3)
Original plan≤ 0.1105-10610~15
DBNPA control scheme0.1~0.2103-1043~4

Microbial control effect:

Under the harsh water quality conditions of the refinery system, DBNPA works synergistically with the bromine-based bactericide to better control the microorganisms. It has a good peeling performance in a system where biological slime breeds severely. After the system uses DBNPA biocide, the cooling tower packing and tower wall are clean, and no sticky mud algae breeds. DBNPA contributes to the maintenance of residual chlorine in bromine-based bactericides.