2-Hydroxy Phosphonoacetic Acid (HPAA)


2-Hydroxy phosphonoacetic acid is chemically stable, hard to hydrolyze, hard to be destroyed by acid or alkali, safe in use, and has no toxicity and pollution. In addition, HPAA can improve zinc solubility. HPAA performs better than commonly used phosphonates like HEDP and EDTMP (5~8 times better).

Sometimes HPAA can even replace molybdate and its derivatives. The good efficiency at low concentrations enables HPAA, usually used at the PPM level. 2-Hydroxy phosphonoacetic acid is water-soluble and can increase Zn solubility. Its effect can be further improved when built with Zn salts or polymer.

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AppearanceDark amber transparent liquid
Solid content, %50.0 Min.
pH (1% solution)3.0 Max.
Density (20℃), g/cm31.30 Min.

The main HPAA production route is as follows.

Phosphorus acid solution reacts with glyoxylic at 100~110℃ for 4~10 hours. And then input water to prepare HPAA aqueous solution. This reaction can be 1-step forward and starts from PCl3 hydrolysis.

Some research studies use microwave irradiation to replace heating to reduce energy consumption and reaction time.


2-Hydroxy phosphonoacetic acid is mainly used as a cathode corrosion inhibitor in the oilfield refill water system in steel & iron, petrochemical, power plant, and medical industries.

When built with zinc salt, the effect is even better. As a corrosion inhibitor, 2-Hydroxy phosphonoacetic acid is mainly applied in the cooling water/industrial water system of oilfields, petrochemical plants, and power plants. It is also used for metal surface treatment in steel.

Packing and storage:

200L plastic drum, IBC (1000L), customers’ requirements.

200L plastic drum 1000L IBC

Storage for one year in a shady room and dry place.

Transport Info:

Corrosive. IMO class 8, UN 3265.


HPA, Hydroxyphosphono-Acetic Acid, Phosphonoglycolic Acid, Belcor 575, Multicor 75, Mayoquest 1750, Unisperse 175, Heparanase-1, Snailagglutinin.